So, now that we know that end is here... almost anyway. 
How do you want the show to end?
Should they kill them off?
Let the Winchesters actually die, and stay dead, finally.
In some last epic battle they sacrifice themselves to save the world. Or something like that.
Let them live happily ever after?
Make them quit the hunter lifestyle, settle down and live a quite life.
Having them continue the fight?
Finish the show with them going away on another case.
Only this time we will not be able to follow them and see it.
Or something else?
Personally I'm actually leaning towards my third option.
Just have them continue the never ending battle.
Think that sounds fitting somehow.
/SK
How do you want the show to end?
Should they kill them off?
Let the Winchesters actually die, and stay dead, finally.
In some last epic battle they sacrifice themselves to save the world. Or something like that.
Let them live happily ever after?
Make them quit the hunter lifestyle, settle down and live a quite life.
Having them continue the fight?
Finish the show with them going away on another case.
Only this time we will not be able to follow them and see it.
Or something else?
Personally I'm actually leaning towards my third option.
Just have them continue the never ending battle.
Think that sounds fitting somehow.
/SK